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TNG 456

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Drug Profile

TNG 456

Alternative Names: TNG-456

Latest Information Update: 12 Dec 2024

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At a glance

  • Originator Tango Therapeutics
  • Class Antineoplastics
  • Mechanism of Action PRMT5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glioblastoma; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 06 Nov 2024 Tango Therapeutics plans a phase I/II trial in Glioblastoma, Non-small cell lung cancer, Solid tumours (Monotherapy, Combination therapy) in the first half of 2025 (unspecified)
  • 06 Nov 2024 Preclinical trials in Glioblastoma (Combination therapy) in USA (unspecified route) prior to November 2024
  • 06 Nov 2024 Preclinical trials in Glioblastoma in USA (unspecified route) (Tango Therapeutics pipeline, November 2024)

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