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PN 8047

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Drug Profile

PN 8047

Alternative Names: Hepcidin mimetic - Protagonist Therapeutics; PN-8047

Latest Information Update: 20 Mar 2026

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At a glance

  • Originator Protagonist Therapeutics
  • Class Small molecules
  • Mechanism of Action Hepcidin replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haemochromatosis; Polycythaemia vera

Most Recent Events

  • 03 Mar 2026 Preclinical trials in Haemochromatosis in USA (PO)
  • 02 Mar 2026 Pharmacokinetic and pharmacodynamic data from preclinical studies released by Protagonist Therapeutics
  • 07 Nov 2024 Protagonist Therapeutics anticipates the nomination of an oral development candidate in the hepcidin mechanism-based haematology program in the first quarter of 2025

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