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DB 1324

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Drug Profile

DB 1324

Alternative Names: DB-1324

Latest Information Update: 10 Dec 2025

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At a glance

  • Originator Duality Biologics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunotoxins
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Gastrointestinal cancer

Most Recent Events

  • 04 Dec 2025 Duality Biologics in collaboration with GlaxoSmithKline plans a phase I/II trial for Gastrointestinal cancer (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater) in USA and Australia (IV) (NCT07263594)
  • 03 Dec 2024 Duality Biologics and GSK entered into an option agreement for rights of DB 1324 in Worldwide excluding China, Hong Kong, Macau for Gastrointestinal cancer
  • 03 Dec 2024 Preclinical trials in Gastrointestinal cancer in China (Parenteral) before December 2024

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