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ISM 5939

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Drug Profile

ISM 5939

Alternative Names: ISM-5939

Latest Information Update: 20 Dec 2024

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At a glance

  • Originator InSilico Medicine
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 12 Dec 2024 InSilico Medicine Hong Kong Limited plans a phase Ia/b trial in Solid tumours (Late-stage disease, Metastatic disease, Monotherapy, Combination therapy) (PO, Tablet), in December 2025(NCT06724042)
  • 21 Nov 2024 Insilico Medicine receives IND clearance from US FDA for ISM 5939 for Solid tumours

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