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AP 003 - Alltrna

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Drug Profile

AP 003 - Alltrna

Alternative Names: AP-003 - Alltrna; Arg-TGA

Latest Information Update: 12 Jul 2026

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At a glance

  • Originator Alltrna
  • Class RNA
  • Mechanism of Action Protein biosynthesis stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Inborn genetic disorders
  • Preclinical Acidaemia; Inborn urea cycle disorders; Phenylketonuria

Most Recent Events

  • 12 Jul 2026 Alltrna plans a phase-II trial for Inborn genetic disorders (Alltrna pipeline; July 2026)
  • 04 May 2026 Phase-I clinical trials in Inborn genetic disorders (In volunteers) in Australia (Parenteral) (ACTRN12626000194369) (Alltrna pipeline; July 2026)
  • 31 Mar 2026 Alltrna receives an approval under Australia's Therapeutic Goods Administration (TGA) Clinical Trial Notification (CTN) scheme to initiate a phase I clinical trial of AP 003 in healthy volunteers in Australia

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