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ZL 6201

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Drug Profile

ZL 6201

Alternative Names: ZL-6201

Latest Information Update: 24 Feb 2026

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At a glance

  • Originator ZAI Lab
  • Class Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors; Hypoxia-inducible factor 1 alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Sarcoma; Solid tumours

Most Recent Events

  • 12 Feb 2026 Phase-I clinical trials in Sarcoma (Late-stage disease, Second-line therapy or greater, Metastatic disease, Inoperable/Unresectable) in USA (Parenteral) (NCT07374848)
  • 12 Feb 2026 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater, Inoperable/Unresectable) in USA (Parenteral) (NCT07374848)
  • 31 Jan 2026 US FDA approves IND application for a global phase I study in patients with sarcoma and potentially other LRRC15-positive solid tumours

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