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NDI 219216

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Drug Profile

NDI 219216

Alternative Names: NDI-219216

Latest Information Update: 06 May 2025

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At a glance

  • Originator Nimbus Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Werner syndrome helicase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from preclinical trials in Solid tumours released by Nimbus Therapeutics
  • 31 Mar 2025 Phase-I/II clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Inoperable/Unresectable, Second-line therapy or greater) in USA (PO) (NCT06898450)
  • 09 Jan 2025 Nimbus plans to initiate a clinical trial for Solid tumours in the first half of 2025

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