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QH 104

Drug Profile

QH 104

Alternative Names: Allogenic B7H3-targeting CAR-γδT cell therapy - Unicet Biotech; QH-104

Latest Information Update: 20 Feb 2025

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At a glance

  • Originator Unicet Biotech
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Glioblastoma

Most Recent Events

  • 13 Feb 2025 Peking University plans a early phase I (phase 0) trial for Solid tumors (Late-stage disease, Second-line therapy or greater) in China (IV) in March 2025 (NCT06825455)
  • 20 Jan 2025 Dushu Lake Hospital Affiliated to Soochow University terminates a phase I/II trial in Glioblastoma (Second-line therapy or greater, Recurrent) in China (Intrathecal) due to the trial cannot be continued for the time being due to the renovation of the hospital premises (NCT06018363)
  • 13 Sep 2024 Efficacy and adverse events data from a phase I/II trial in Glioblastoma presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)

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