QH 104
Alternative Names: Allogenic B7H3-targeting CAR-γδT cell therapy - Unicet Biotech; QH-104Latest Information Update: 20 Feb 2025
At a glance
- Originator Unicet Biotech
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Glioblastoma
Most Recent Events
- 13 Feb 2025 Peking University plans a early phase I (phase 0) trial for Solid tumors (Late-stage disease, Second-line therapy or greater) in China (IV) in March 2025 (NCT06825455)
- 20 Jan 2025 Dushu Lake Hospital Affiliated to Soochow University terminates a phase I/II trial in Glioblastoma (Second-line therapy or greater, Recurrent) in China (Intrathecal) due to the trial cannot be continued for the time being due to the renovation of the hospital premises (NCT06018363)
- 13 Sep 2024 Efficacy and adverse events data from a phase I/II trial in Glioblastoma presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)