VY 2149
Alternative Names: VY-2149Latest Information Update: 14 May 2025
At a glance
- Originator Vivoryon Therapeutics
- Class Small molecules; Urologics
- Mechanism of Action Glutaminyl-peptide cyclotransferase inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Preclinical Kidney disorders
- Research Diabetic nephropathies
Most Recent Events
- 29 Apr 2025 Vivoryon Therapeutics has patent pending for medical use for varoglutamstat and backup compounds/VY2149, as well as on dosing regimens and on the use of varoglutamstat and related structures (e.g. VY2149) for the treatment of kidney diseases
- 29 Apr 2025 Vivoryon Therapeutics has patent pending for QPCT/L inhibitors (varoglutamstat and VY2149) in combination with SGLT2 inhibitors
- 04 Mar 2025 Vivoryon Therapeutics plans a phase IIb trial for Type 2 diabetes mellitus and diabetic nephropathies