Drug Profile

BGB B455

Alternative Names: BGB-B455

Latest Information Update: 14 Jun 2025

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At a glance

Originator BeiGene
Developer BeOne Medicines
Class Antineoplastics; Bispecific antibodies; Immunotherapies
Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

18 Mar 2025 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Metastatic disease, Late-stage disease, Monotherapy) in Australia (Parenteral) (NCT06803680)
31 Jan 2025 BeiGene plans a phase I trial for Solid tumours (Late-stage disease, Monotherapy, Metastatic disease, Inoperable/unresectable) in unknown location (Parenteral) in March 2025 (NCT06803680)
31 Jan 2025 Preclinical trials in Solid tumours in China (Parenteral) prior to January 2025

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