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APX 343A

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Drug Profile

APX 343A

Alternative Names: APX-343A

Latest Information Update: 26 Nov 2025

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At a glance

  • Originator AptaBio Therapeutics
  • Class Antineoplastics
  • Mechanism of Action CYBB protein inhibitors; NOX1 protein inhibitors; NOX4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Solid tumours
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 24 Oct 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater, Combination therapy) in South Korea (PO) (NCT07123415)
  • 24 Oct 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater, Monotherapy) in South Korea (PO) (NCT07123415)
  • 15 Sep 2025 Aptabio Therapeutics plans a phase I trial for (Late-stage disease, Monotherapy, Combination therapy) in South Korea (PO), in October 2025 (NCT07123415)

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