Drug Profile

LCA 0321

Alternative Names: LCA-0321

Latest Information Update: 21 Aug 2026

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At a glance

Originator Lycia Therapeutics
Class Eye disorder therapies
Mechanism of Action Thyroid-stimulating immunoglobulin inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Graves' disease
Preclinical Graves ophthalmopathy

Most Recent Events

02 Apr 2026 Phase-I clinical trials in Graves' disease (In volunteers) in Netherlands (unspecified route) (CTIS2025-524053-14-00)
17 Mar 2026 Lycia Therapeutics plans a phase I trial for Graves disease in Netherlands in April 2026 (CTIS2025-524053-14-00)
11 Feb 2025 Preclinical trials in Graves ophthalmopathy in USA (unspecified route) prior to February 2025 (Lycia Therapeutics Pipeline, February 2025)

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