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BR 111

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Drug Profile

BR 111

Alternative Names: BR-111

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator BioRay Pharmaceutical
  • Class 2 ring heterocyclic compounds; Antineoplastics; Cyclic ethers; Drug conjugates; Furans; Immunoconjugates; Ketones; Macrocyclic compounds; Monoclonal antibodies; Small molecules
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Solid tumours

Most Recent Events

  • 28 Feb 2025 Pharmacodynamics data from preclinical studies in Hematological malignancies and Solid tumors presented at American Association for Cancer Research Annual Meeting 2024 (AACR-2024)
  • 10 Feb 2025 NMPA accepts CTA application for BR 111 in Hematolgical malignancies and Solid tumors
  • 22 Mar 2024 Preclinical trials in Haematological malignancies in China (Parenteral)

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