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ALN 4324

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Drug Profile

ALN 4324

Alternative Names: ALN-4324

Latest Information Update: 25 Feb 2026

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At a glance

  • Originator Alnylam Pharmaceuticals
  • Class Antihyperglycaemics; Ribonucleosides; Small interfering RNA
  • Mechanism of Action GRB14 protein expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Type 2 diabetes mellitus

Most Recent Events

  • 16 Feb 2026 Phase-II clinical trials in Type 2 diabetes mellitus in USA (SC)
  • 15 Jan 2026 Alnylam Pharmaceuticals initiates a phase II trial for Type 2 diabetes mellitus in the USA (SC) (NCT07465224)
  • 11 Jan 2026 Alnylam plans a phase II trial for Type 2 diabetes mellitus in 1H of 2026

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