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PLX 61639

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Drug Profile

PLX 61639

Alternative Names: PLX-61639

Latest Information Update: 22 Dec 2025

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At a glance

  • Originator Plexium
  • Class Antineoplastics; Small molecules
  • Mechanism of Action SMARCA2 protein degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 02 Dec 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT07284186)
  • 27 Feb 2025 Preclinical trials in Solid tumours in USA (PO) prior to February 2025 (Plexium pipeline, February 2025)

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