Drug Profile

ENX 205

Latest Information Update: 31 Mar 2025

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At a glance

Originator Engrail Therapeutics
Class Anxiolytics; Mood stabilisers
Mechanism of Action 5-HT1A serotonin receptor agonists; Dopamine D2 receptor antagonists; Dopamine D3 receptor antagonists; Serotonin 5-HT2A receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Feb 2025 Preclinical trials in Mood disorders in USA (unspecified route) (Engrail Therapeutics pipeline, February 2025)
28 Feb 2025 Preclinical trials in Post-traumatic stress disorders in USA (unspecified route) (Engrail Therapeutics pipeline, February 2025)

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