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Research programme: JAK2 V617F mutant-selective inhibitors - Atavistik Bio

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Drug Profile

Research programme: JAK2 V617F mutant-selective inhibitors - Atavistik Bio

Latest Information Update: 09 Dec 2025

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At a glance

  • Originator Atavistik Bio
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Janus kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Myeloproliferative disorders

Most Recent Events

  • 04 Dec 2025 Pharmacodynamics data from a preclinical trials in Myeloproliferative disorders released by Atavistik Bio
  • 20 Mar 2025 Preclinical trials in Myeloproliferative disorders in USA (unspecified route) (Atavistik Bio pipeline, March 2025)

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