Drug Profile

INCB 177054

Alternative Names: INCB-177054

Latest Information Update: 05 May 2025

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At a glance

Originator Incyte Corporation
Class Antineoplastics
Mechanism of Action DGKZ protein inhibitors; Diacylglycerol kinase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Solid tumours

Most Recent Events

25 Apr 2025 Pharmacodynamics data from preclinical trials in Solid tumours released by Incyte Corporation
23 Mar 2025 Incyte Corporation plans a phase I/II trial in Solid tumours (Combination therapy, Metastatic disease, Late-stage disease, Second-line therapy and greater) in USA (PO), in April 2025 (NCT06873789),
18 Mar 2025 Preclinical trials in Solid tumours in USA (PO), before March 2025

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