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YL 217

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Drug Profile

YL 217

Alternative Names: YL-217

Latest Information Update: 29 Jul 2025

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At a glance

  • Originator MediLink Therapeutics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 02 Jul 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA, China (IV-infusion) (NCT06859762)
  • 25 Apr 2025 Pharmacodynamics, pharmacokinetics and adverse events data from preclinical studies in Solid tumors presented at 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Mar 2025 MediLink Therapeutics plans a phase I clinical trial in Solid tumours (Late-stage disease) in US in May 2025 (IV, infusion) (NCT06859762)

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