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mRNA 4106

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Drug Profile

mRNA 4106

Alternative Names: mRNA-4106

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator Moderna Therapeutics
  • Class Antineoplastics; Immunotherapies; RNA
  • Mechanism of Action Protein biosynthesis stimulants; RNA replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 26 Mar 2025 Preclinical trials in Solid tumours in USA (IM), prior to March 2025 (Moderna Therapeutics website, March 2025)
  • 25 Mar 2025 Phase-I clinical trials in Solid tumours (Combination therapy, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater, Late-stage disease) in USA (IM) (NCT06880549)
  • 25 Mar 2025 Phase-I clinical trials in Solid tumours (Monotherapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater) in USA (IM) (NCT06880549)

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