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mRNA 4106

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Drug Profile

mRNA 4106

Alternative Names: mRNA-4106

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator Moderna Therapeutics
  • Class Antineoplastics; RNA
  • Mechanism of Action RNA replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 26 Mar 2025 Preclinical trials in Solid tumours in USA (IM), prior to March 2025 (Moderna Therapeutics website, March 2025)
  • 25 Mar 2025 Moderna Therapeutics plans the phase I mRNA-4106-P101 trial for Solid tumours (Monotherapy, Combination therapy, Late-stage disease, Metastatic disease, -line therapy or greater, Inoperable/Unresectable) in USA (IM, Injection) (NCT06880549)
  • 14 Mar 2025 Moderna Therapeutics plans a phase I trial for Solid tumours (Monotherapy, Combination therapy, Late-stage disease, Metastatic disease, First-line therapy, Second-line therapy or greater, Inoperable/Unresectable) in USA (IM) (NCT06880536)

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