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KH 815

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Drug Profile

KH 815

Alternative Names: KH-815

Latest Information Update: 20 Jun 2025

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At a glance

  • Originator Chengdu Kanghong Biotech
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors; RNA polymerase II inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 May 2025 Pharmacodynamic and adverse events data from a preclinical studies in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 20 May 2025 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in China (IV) (NCT06885645) (CTR20251646)
  • 28 Mar 2025 Chengdu Kanghong Biotech plans phase Ia/Ib trial in Solid tumours (Late-stage disease, Second-line therapy and greater and Inoperable/ Unresectable) in April 2025 (IV) (NCT06885645)

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