Drug Profile

NPX 125

Alternative Names: B7-H7-ADC; B7-H7-targeted antibody drug conjugate - NextPoint Therapeutics; NPX-125

Latest Information Update: 01 Jul 2025

Price :

$50 ^*

Note:

Adis is an information provider. We do not sell or distribute actual drugs.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

Originator NextPoint Therapeutics
Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
Mechanism of Action DNA topoisomerase I inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Cancer

Most Recent Events

01 Jul 2025 Pharmacokinetics and pharmacodynamics data from a preclinical trial in Cancer presented at the 116^th Annual Meeting of the American Association for Cancer Research (AACR-2025)
25 Apr 2025 Nextpoint Therapeutics plans a clinical trial for Cancer (Parenteral)
25 Apr 2025 NextPoint Therapeutics plans to file an IND application with the US FDA for Cancer

You need to be a logged in or subscribed to view this content

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com