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XS 03

Drug Profile

XS 03

Alternative Names: XS-03

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator XSXH Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Polo-like kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Colorectal cancer

Most Recent Events

  • 20 Apr 2025 XSXH Therapeutics in collaboration with NovaOnco Therapeutics plans a phase I/II trial for Colorectal cancer (Combination therapy, Late-stage disease, Metastatic disease) in China (PO), in June 2025 (NCT06936527)
  • 27 Feb 2025 Preclinical trials in Colorectal cancer in China (PO), prior to February 2025
  • 27 Feb 2025 The National Medical Products Administration (NMPA) approves clinical trial application for XS 03 in Colorectal cancer (Combination therapy, Late-stage disease, Metastatic disease) in China

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