Drug Profile

5 flurouracil topical - SiSaf

Alternative Names: SIS-022

Latest Information Update: 04 Jul 2025

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At a glance

Originator SiSaf
Class Antineoplastics; Pyrimidinones; Skin disorder therapies; Small molecules
Mechanism of Action DNA synthesis inhibitors; Thymidylate synthase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

06 May 2025 Preclinical trials in Actinic keratosis in United Kingdom (Topical), before May 2025 (SiSaf pipeline, May 2025)
06 May 2025 Preclinical trials in Hypertrophic scars in United Kingdom (Topical), before May 2025 (SiSaf pipeline, May 2025)
06 May 2025 Preclinical trials in Skin cancer in United Kingdom (Topical), before May 2025 (SiSaf pipeline, May 2025)

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