Drug Profile

ZL 1222

Alternative Names: ZL-1222

Latest Information Update: 20 Jun 2025

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At a glance

Originator ZAI Lab
Class Antibodies; Antineoplastics; Cytokines; Immunoglobulin Fc fragments; Immunoglobulin fusion proteins; Immunotherapies; Interleukins; Recombinant fusion proteins
Mechanism of Action Antibody-dependent cell cytotoxicity; Interleukin 12 stimulants; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

25 Apr 2025 Pharmacodynamics data from preclinical studies in Cancer presented at 116^thAnnual Meeting of the American Association for Cancer Research (AACR-2025)
26 Mar 2025 Preclinical trials in Cancer in China (Parenteral), prior to March 2025

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