Drug Profile

Ataciguat - Kardigan

Latest Information Update: 08 Oct 2025

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At a glance

Originator Kardigan
Class Anthranilic acids; Benzamides; Cardiovascular therapies; Chlorobenzenes; Morpholines; Small molecules; Sulfonamides; Thiophenes
Mechanism of Action Guanylate cyclase stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

11 Jun 2025 Kardigan plans a phase III KATALYST-AV trial for Aortic valve stenosis in June 2025 (NCT07001800)
03 Jun 2025 Preclinical trials in Aortic valve stenosis in USA (unspecified route) before June 2025

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