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CLD 401

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Drug Profile

CLD 401

Alternative Names: CLD-401

Latest Information Update: 11 Feb 2026

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At a glance

  • Originator Calidi Biotherapeutics
  • Class Antineoplastics; Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action CD55 antigen stimulants; Cell death stimulants; Immunologic cytotoxicity; Interleukin 15 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 28 Jan 2026 Calidi Biotherapeutics plans a phase I trial for Solid tumours
  • 30 Oct 2025 Calidi Biotherapeutics plans to file an Investigational New Drug (IND) application by the end of 2026.
  • 03 Jun 2025 Early research in Solid tumours in USA (IV), Prior to June 2025

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