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REX 8756

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Drug Profile

REX 8756

Alternative Names: REX-8756; SAR-448755

Latest Information Update: 22 Dec 2025

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At a glance

  • Originator Recludix Pharma
  • Class Anti-inflammatories; Antiasthmatics; Skin disorder therapies; Small molecules
  • Mechanism of Action STAT6 transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Asthma; Atopic dermatitis; Chronic obstructive pulmonary disease

Most Recent Events

  • 16 Dec 2025 US FDA approves IND application for REX 8756 for phase-I trial in Asthma, Chronic obstructive pulmonary disease (COPD) and Atopic dermatitis (In volunteers) (PO)
  • 16 Dec 2025 Recludix Pharma plans phase-I trial for Asthma, Chronic obstructive pulmonary disease (COPD) and Atopic dermatitis (In volunteers) (PO)
  • 14 Jun 2025 Recludix Pharma and Sanofi agree to co-develop STAT6 transcription factor inhibitors for multiple immunological and inflammatory indications

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