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HSK 47977

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Drug Profile

HSK 47977

Alternative Names: HSK-47977

Latest Information Update: 23 Dec 2025

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At a glance

  • Originator Haisco Pharmaceutical Group
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto oncogene proteins c-bcl-6 degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-Hodgkin's lymphoma
  • Preclinical Diffuse large B cell lymphoma

Most Recent Events

  • 28 Aug 2025 Phase-I clinical trials in Non-Hodgkin's lymphoma (Second-line therapy or greater) in China (PO) (NCT07283796)
  • 25 Apr 2025 Preclinical trials in Diffuse large B cell lymphoma in China (PO), prior to April 2025
  • 25 Apr 2025 Pharmacodynamics and pharmacokinetics data from a preclinical trial in Diffuse large B cell lymphoma presented at the 116th Annual Meeting of the American Association for Cancer Research 2025 (AACR-2025)

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