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GenSci 140

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Drug Profile

GenSci 140

Alternative Names: GenSci-140

Latest Information Update: 08 Jan 2026

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At a glance

  • Originator GeneScience Pharmaceuticals
  • Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 10 Dec 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in China (Parenteral) (NCT07251166)
  • 26 Nov 2025 GeneScience Pharmaceuticals plans a first-in-human phase I trial for Solid tumours and Ovarian cancer (Late-stage disease) in China (Parenteral, Injection), in December 2025 (NCT07251166)
  • 25 Apr 2025 Preclinical trials in Solid tumours in China (Parenteral), prior to April 2025

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