Drug Profile

TM4SF1 - cMET bispecific antibody drug conjugate - Tavotek Biotherapeutics

Alternative Names: Bispecific TM4SF1-cMET MMAE - Tavotek Biotherapeutics; TM4SF1 - cMET bispecific ADC - Tavotek Biotherapeutics

Latest Information Update: 26 Jun 2025

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At a glance

Originator Tavotek Biotherapeutics
Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates
Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

25 Apr 2025 Preclinical trials in Solid tumours in USA (Parenteral)
25 Apr 2025 Pharmacodynamics data from a Preclinical trials in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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