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KT 485

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Drug Profile

KT 485

Alternative Names: KT-485; SAR-447971

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator Kymera Therapeutics
  • Developer Kymera Therapeutics; Sanofi
  • Class Anti-inflammatories; Antirheumatics; Skin disorder therapies; Small molecules
  • Mechanism of Action Interleukin-1 receptor-associated kinase degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Asthma; Atopic dermatitis; Hidradenitis suppurativa; Inflammatory bowel diseases; Rheumatoid arthritis

Most Recent Events

  • 25 Jun 2025 Preclinical trials in Asthma in USA (PO)
  • 25 Jun 2025 Preclinical trials in Atopic dermatitis in USA (PO)
  • 25 Jun 2025 Preclinical trials in Hidradenitis suppurativa in USA (PO)

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