Drug Profile

AUBE 00

Alternative Names: AUBE-00

Latest Information Update: 30 Aug 2026

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At a glance

Originator Chugai Pharmaceutical
Class Antineoplastics; Cyclic peptides
Mechanism of Action KRAS protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

22 Apr 2026 Pharmacokinetic and pharmacodynamics data from a preclinical studies in Solid tumour presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR 2026)
27 Jun 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Monotherapy) in the USA and Japan (PO) (NCT07030959)
27 Jun 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Combination therapy) in Japan (PO) (NCT07030959)

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