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APL 045

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Drug Profile

APL 045

Alternative Names: APL-045

Latest Information Update: 23 Jul 2025

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At a glance

  • Originator Apollo Therapeutics
  • Class Antineoplastics
  • Mechanism of Action EIF-2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 30 Jun 2025 Pharmacodynamics and pharmacokinetics data from preclinical trials in cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Preclinical trials in Cancer in United Kingdom (unspecified route)
  • 25 Apr 2025 Apollo Therapeutics plans IND enabling studies for APL 045

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