Drug Profile

CEACAM5xCDH17xCD3 T cell engager therapeutic - Helixon

Latest Information Update: 28 Nov 2025

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At a glance

Originator Helixon US
Class Antineoplastics; Immunotherapies; Recombinant fusion proteins; Trispecific antibodies
Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

25 Apr 2025 Preclinical trials in Colorectal cancer in USA (Parenteral), prior to April 2025
25 Apr 2025 Pharmacodynamics data from a preclinical trial in Colorectal cancer presented at the 116^thAnnual Meeting of the American Association for Cancer Research (AACR-2025)

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