Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

HT VA

Next Previous
Drug Profile

HT VA

Alternative Names: GDNF based therapy - Hoth Therapeutics/Silo Pharma; HT-VA

Latest Information Update: 30 Jul 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Hoth Therapeutics; Silo Pharma
  • Class Hepatoprotectants; Obesity therapies
  • Mechanism of Action Glial cell line-derived neurotrophic factor receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Non-alcoholic fatty liver disease; Obesity

Most Recent Events

  • 25 Jul 2025 Hoth Therapeutics establishes CRADA with the United States Department of Veterans Affairs and Foundation for Atlanta Veterans Education and Research for the development of GDNF based therapy in Obesity and Fatty liver disease
  • 25 Jun 2025 Hoth Therapeutics and Silo Pharma agree to co-develop GDNF based therapy in-licensed from US Department of Veteran Affairs for Obesity and Nonalcoholic fatty liver disease
  • 25 Jun 2025 Preclinical trials in Non-alcoholic fatty liver disease in USA (Parenteral) before June 2025

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top