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HLA-A02 TP53-R175H targeting T cell engager - Affini-T Biotherapeutics

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Drug Profile

HLA-A02 TP53-R175H targeting T cell engager - Affini-T Biotherapeutics

Alternative Names: P53 R175H targeting bispecific T cell engager - Affini-T Biotherapeutics ; T cell engager targeting HLA-A 02 01 TP53-R175H - Affini-T Biotherapeutics

Latest Information Update: 30 Jul 2025

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At a glance

  • Originator Affini-T Therapeutics
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 25 Apr 2025 Preclinical trials in Cancer in USA (Parenteral) before April 2025
  • 25 Apr 2025 Pharmacodynamics data from preclinical studies in Cancer were presented at 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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