Drug Profile

DXTX 1464

Alternative Names: DXTX-1464

Latest Information Update: 24 Sep 2025

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At a glance

Originator Differentiated Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action CCNE1 protein degraders; CCNE2 protein degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Cancer

Most Recent Events

25 Apr 2025 Preclinical trials in Cancer in USA (unspecified route) prior to April 2025
25 Apr 2025 Pharmacodynamics and adverse events data from a preclinical study in Cancer presented at the 116^th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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