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PIN 5018

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Drug Profile

PIN 5018

Alternative Names: PIN-5018

Latest Information Update: 15 Dec 2025

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At a glance

  • Originator Pin Therapeutics
  • Class Antineoplastics; Peptides
  • Mechanism of Action Casein kinase lalpha degraders; Proteolysis
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Adenoid cystic carcinoma
  • Preclinical Acute myeloid leukaemia; Solid tumours

Most Recent Events

  • 24 Nov 2025 Phase-I clinical trials in Adenoid cystic carcinoma (PO)
  • 17 Jul 2025 US FDA approves IND application for PIN 5018 in Solid tumours
  • 17 Jul 2025 Pharmacodynamics data from a preclinical trial in Solid tumours released by Pin Therapeutics (Pin Therapeutics website, July 2025)

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