Drug Profile

Claudin18.2 targeting CAR-T cell therapy - Essen Biotech

Latest Information Update: 21 Jul 2025

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At a glance

Originator Essen BioTech
Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

17 Jul 2025 Phase I/II trials in Pancreatic cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT07066995)

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