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ASP 5834

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Drug Profile

ASP 5834

Alternative Names: ASP-5834

Latest Information Update: 19 Feb 2026

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At a glance

  • Originator Astellas Pharma
  • Class Antineoplastics
  • Mechanism of Action KRAS protein degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 04 Feb 2026 ASP 5834 receives Fast track status from the US FDA for Non-small cell lung cancer (Astellas Pharma pipeline, February 2026)
  • 31 Jul 2025 Astellas Pharma plans a phase I trial for Solid tumor (Late-stage disease, Metastatic disease, Monotherapy, Combination therapy) in July 2025 (IV) (NCT07094204)
  • 30 Jul 2025 Preclinical trials in Solid tumours in Japan (IV)

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