Drug Profile

Abz 495

Alternative Names: Abz-495

Latest Information Update: 23 Sep 2025

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At a glance

Originator Abzyme Therapeutics
Class Antineoplastics; Bispecific antibodies; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins
Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

03 Sep 2025 Abz 495 is available for licensing as of 03 Sep 2025. https://abzymetx.com/immuno-oncology-preclin-pipe/
03 Sep 2025 Preclinical trials in Cancer in USA (Parenteral) (Abzyme Therapeutics pipeline, September 2025)
15 Oct 2024 Abzyme Therapeutics has patent protection for antibodies binding to human CD3 at acidic pH in the US

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