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VGT 1849B

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Drug Profile

VGT 1849B

Alternative Names: VGT-1849B

Latest Information Update: 21 Nov 2025

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At a glance

  • Originator Vanda Pharmaceuticals
  • Class Antineoplastics; Antisense oligonucleotides
  • Mechanism of Action Janus kinase 2 inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Polycythaemia vera
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Polycythaemia vera

Most Recent Events

  • 28 Aug 2025 Preclinical trials in Polycythaemia vera in USA (unspecified route), prior to September 2025
  • 28 Aug 2025 VGT 1849B receives Orphan Drug status for Polycythaemia vera in USA

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