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ABBV 166

Drug Profile

ABBV 166

Alternative Names: ABBV-066 + ABT-981; ABBV-166; Risankizumab + lutikizumab

Latest Information Update: 31 Oct 2025

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At a glance

  • Originator AbbVie
  • Class Anti-inflammatories; Antiasthmatics; Antipsoriatics; Antirheumatics; Bispecific antibodies; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin 1 alpha inhibitors; Interleukin 1 beta inhibitors; Interleukin-23 subunit p19 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Crohn's disease; Psoriatic arthritis

Most Recent Events

  • 11 Apr 2025 Phase-II clinical trials in Psoriatic arthritis (Combination therapy, Treatment-resistant) in Poland, France, Hungary, Czech Republic, USA, Canada (SC) (NCT06865105)
  • 04 Sep 2024 Phase-II clinical trials in Crohn's disease (Combination therapy, Treatment-resistant) in United Kingdom, Turkey, Taiwan, Switzerland, Spain, South Korea, Slovenia, Slovakia, Singapore, Serbia, Romania, Portugal, Poland, Norway, Netherlands, Lithuania, Latvia, Italy, Ireland, Israel, Hungary, Germany, France, Estonia, Czech Republic, Croatia, Canada, Bulgaria, Belgium, Austria, USA (SC) (NCT06548542)

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