Drug Profile

OTS 412

Alternative Names: mOTS-412; OTS-412

Latest Information Update: 28 Nov 2025

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At a glance

Originator Bionoxx
Class Antineoplastics; Immunotherapies; Oncolytic viruses
Mechanism of Action Cell death stimulants; Immunologic cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Preclinical Solid tumours

Most Recent Events

30 Sep 2025 Bionoxx plans a phase I trial for Solid tumours (Second line therapy or greater, Monotherapy, Combination therapy) in South Korea in November 2025 (NCT07190833)
16 Sep 2025 Preclinical trials in Solid tumours in South Korea (Intratumoural)
10 Sep 2025 Bionoxx plans a phase I trial for Solid tumours (Combination therapy, Second-line therapy or greater) (Intratumoural) in December 2025 (NCT07170592)

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