Drug Profile

CDX 0239 PBD

Alternative Names: CDX-0239-PBD

Latest Information Update: 09 Dec 2025

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At a glance

Originator Celldex Therapeutics Inc; The Childrens Hospital of Philadelphia
Developer Celldex Therapeutics Inc
Class Antibodies; Antineoplastics; Benzodiazepines; Drug conjugates; Immunoconjugates; Pyrroles
Mechanism of Action DNA cross linking agents

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

15 Aug 2025 Preclinical trials in Solid tumours in USA (Parenteral) prior to August 2025
15 Aug 2025 Pharmacodynamics data from the preclinical trials in Solid tumours is released by Celldex Therapeutics
15 Aug 2025 Celldex and Children's Hospital of Philadelphia plans a early phase clinical trial (In children) in Solid tumours

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