Balomenib - Clywedog Therapeutics
Alternative Names: CLY-101Latest Information Update: 23 Dec 2025
At a glance
- Originator Clywedog Therapeutics
- Class Antihyperglycaemics; Small molecules
- Mechanism of Action Glucagon-like peptide inhibitors; Menin inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Type 1 diabetes mellitus; Type 2 diabetes mellitus
Most Recent Events
- 17 Dec 2025 Clywedog Therapeutics initiates a phase Ib trial for Type 2 diabetes mellitus (PO)
- 30 Sep 2025 Clywedog Therapeutics receives a formal regulatory authorization for a phase Ib trial of balomenib for the treatment of Type 2 diabetes mellitus
- 30 Sep 2025 Phase-I clinical trials in Type 1 diabetes mellitus (In volunteers) in USA (PO)