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MRGPRX2 inhibitor - Arcus Biosciences

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Drug Profile

MRGPRX2 inhibitor - Arcus Biosciences

Latest Information Update: 05 Mar 2026

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At a glance

  • Originator Arcus Biosciences
  • Class Skin disorder therapies; Small molecules
  • Mechanism of Action MRGPRX2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Atopic dermatitis; Chronic urticaria

Most Recent Events

  • 25 Feb 2026 Arcus Biosciences plans a clinical trial (In volunteers) (PO), in 2026
  • 06 Oct 2025 Arcus Biosciences plans a clinical trial in Atopic dermatitis and Chronic urticaria (PO) in 2026
  • 06 Oct 2025 Preclinical trials in Atopic dermatitis in USA (PO), prior to October 2025

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