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MRGPRX2 inhibitor - Arcus Biosciences

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Drug Profile

MRGPRX2 inhibitor - Arcus Biosciences

Latest Information Update: 04 Dec 2025

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At a glance

  • Originator Arcus Biosciences
  • Class Skin disorder therapies; Small molecules
  • Mechanism of Action MRGPRX2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Atopic dermatitis; Chronic urticaria

Most Recent Events

  • 06 Oct 2025 Preclinical trials in Atopic dermatitis in USA (unspecified route), prior to October 2025
  • 06 Oct 2025 Preclinical trials in Chronic-urticaria in USA (unspecified route), prior to October 2025
  • 06 Oct 2025 Arcus Biosciences plans a clinical trial for Atopic dermatitis and Chronic urticaria in 2026

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