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MNA 001

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Drug Profile

MNA 001

Alternative Names: MNA-001; MTX-46943

Latest Information Update: 07 Sep 2026

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At a glance

  • Originator Muna Therapeutics
  • Class Antidementias; Small molecules
  • Mechanism of Action TREM2 protein-stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Alzheimer's disease

Most Recent Events

  • 09 Jul 2026 Muna Therapeutics completes phase-I clinical trials in Alzheimer's disease (In volunteers) in Netherlands (PO) (CTIS2025-522368-34-00)
  • 30 Jun 2026 Muna Therapeutics plans a phase-II trial for Alzheimer's disease in early 2027 (PO)
  • 05 Sep 2025 Phase-I clinical trials in Alzheimer's disease (In volunteers) in Netherlands (PO) (CTIS2025-522368-34-00)

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