Drug Profile

MTX 46943

Alternative Names: MTX-46943

Latest Information Update: 13 Oct 2025

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At a glance

Originator Muna Therapeutics
Class Antidementias; Small molecules
Mechanism of Action TREM2 protein-stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Alzheimer's disease

Most Recent Events

05 Sep 2025 Phase-I clinical trials in Alzheimer's disease (In volunteers) in Netherlands (unspecified route) (CTIS2025-522368-34-00)
05 Sep 2025 Preclinical trials in Alzheimer's disease in Denmark (unspecified route) before September 2025 (Muna Therapeutics pipeline, September 2025)
29 Jul 2025 Pharmacodynamics data from a preclinical trial in Alzheimer's disease released by Muna Therapeutics

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